The Maoshan area is an area with well-developed igneous rocks and complex structures. The thickness of the reservoirs is generally small. The study of the reservoirs is based on seismic data, logging data and geological data. Using techniques and software such as Voxelgeo, BCI, RM, DFM and AP, the authors have made a comprehensive analysis of the lateral variation of reservoir parameters in the Upper Shazu bed of the third member of the Palaeogene Funing Formation, and compiled the thickness map of the Shazu bed. Also, with the data from ANN, BCI and the abstracting method for seismic characteristic parameters in combination with the structural factors, the authors have tried the multi-parameter and multi-method prediction of petroleum, delineated the potential oil and gas areas and proposed two well sites. The prediction of oil and gas for Well JB2 turns out to be quite successful.