Li4Ti5O12 powders were prepared by so-gel method using tetrabutyl titanate, lithium acetate and absolute alcohol as starting materials. Li4Ti5O12-polyaniline (Li4Ti5O12-PAn) composite was prepared by in situ polymerization method using aniline, ammonium persulfate and hydrochloricarried as starting materials. Li4Ti5O12-PAn composite was characterized by X-ray diffractometry (XRD), infrared spectrum (IR) combined with electrochemical tests. The results show that the electrical conductivity is enhanced obviously due to the introduction of PAn to Li4Ti5O12. Li4Ti5O12-PAn composite exhibits better high-rate capability and cyclability than Li4Ti5O12. The composite can deliver a specific capacity of 191.3 and 148.9 mA·h/g, only 0.13% and 0.61% of the capacity is lose after being discharged 80 times at 0.1C and 2.0C, respectively.