Objective To investigate an effective method to facilitate the physical and mental recovery of drug abusers in detoxification restoration period. Methods Integrated interventions were adopted to observe the changes in the physical and mental conditions of female drug abusers who had withdrawn drugs. Results Comparing behavioral changes between the two groups before and after intervention, we found that changes of score in the intervention group were all higher than those in the control group in terms of their physical symptoms or state of anxiety. Conclusion It is necessary to help drug abusers understand the harm of drug-abuse, build up self-confidence and improve EQ through interventions, It will be beneficial for the drug addicts to refrain from drug-taking and regain a normal life. Our study has proved that positive results can only be obtained from integrated intervention projects.