Adriamycin increases podocyte permeability: evidence and molecular mechanism

期刊名字：中華醫(yī)學雜志（英文版）
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論文作者：李曉忠，袁海濤，張學光
作者單位：Institute of Biotechnology Affiliated with Soochow University,Nephro-Urology Unit
更新時間：2023-02-26
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論文簡介

Objective To investigate the increased podocyte permeability by evidence of adriamycin (AD) and its molecular mechanism.Methods In this study, we explored the direct effects of AD on cultured mouse podocytes and the potential protection effects of Dexamethasome (Dex).Results After 24-hour AD (5×10-7 mol/L) treatment, albumin passage through podocyte monolayers was increased by 2.27-fold (P

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