Tetra-n-butylammonium Hydroxide: an Efficient Catalyst for N-Alkylation of Pyrimidines and Purines

期刊名字：高等學?；瘜W研究（英文版）
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論文作者：ZHANG Zhi-li，ZHOU Shou-xin，WAN
作者單位：Department of Chemical Biology,State Key Laboratory of Natural and Biomimetic Drugs
更新時間：2022-12-12
下載次數(shù)：次

論文簡介

An efficient procedure for N-alkylation of pyrimidines and purines in the presence of tetra-n-butylammonium hydroxide(TBAH) is described. The method is very practical and the alkylation can occur at room temperature and the yields of the N-alkyl pyrimidines and purines were found to be excellent.

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