The numerical calculation method is widely used in the evaluation of slope stability, but it cannot take the randomness and fuzziness into account that exist in rock and soil engineering objectively. The fuzzy optimization theory is thus introduced to the evaluation of slope stability by this paper and a method of fuzzy optimal selection of similar slopes is put forward to analyze slope stability. By comparing the relative membership degrees that the evaluated object sample of slope is similar to the source samples of which the stabilities are detected clearly, the source sample with the maximal relative membership degree will be chosen as the best similar one to the object sample, and the stability of the object sample can be evaluated by that of the best similar source sample. In the process many uncertain influential factors are considered and characteristics and knowledge of the source samples are obtained. The practical calculation indicates that it can achieve good results to evaluate slope stability by using this method.