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Evaluation of The Interaction between Netropsin and Double Stranded DNA by Capillary Zone Electropho Evaluation of The Interaction between Netropsin and Double Stranded DNA by Capillary Zone Electropho

Evaluation of The Interaction between Netropsin and Double Stranded DNA by Capillary Zone Electropho

  • 期刊名字:中國(guó)化學(xué)快報(bào)
  • 文件大?。?/li>
  • 論文作者:Xin Ya HE,Da Zhi LI,Ai Ye LIAN
  • 作者單位:Dalian Institute of Chemical Physics
  • 更新時(shí)間:2023-04-17
  • 下載次數(shù):
論文簡(jiǎn)介

Capillary zone electrophoresis (CZE) was applied to study the interaction between netropsin and a 14mer double stranded DNA (dsDNA). The binding constant of this interaction calculated from Scatchard plot was (1.07±0.10)×105 (mol/L)-1. The binding stoichiometry was 1:1. The use of polyacrylamide coated capillary showed better effect in the analysis of DNA than noncoated capillary.

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