An innovative internal circulation membrane bioreactor( ICMBR)treating traditional opaque beer brewery wastewater was introduced. Beer wastewater from Tianjin Huarun Brewhouse wastaken as the influent. The removal efficiency of suspended solid, chemical oxygen demand, total nitrogen and ammonia nitrogen were studied with the changeable hard real time design method, organic loading rate and nutrition elements. The average percentage reduction in chemical oxygen demand achieved 90%. The total nitrogen and ammonia nitrogen were also reduced by 90% and 95%,respectively. The results indicate that the outlet of ICMBR meets the requirements of the environment landscape recycling use.