Circumstance influence factors on Hybrid Membrane Bio-Reactor (HMBR) process for the wastewater reclamation in dwelling district was analyzed. The main characteristic of this process is that sludge and nitrified effluent can be recycled automatically, which simplifies the operation of system and is beneficial to get the high removal of organics and nitrogen. Based on the analysis of circumstance influence factors, it is recommended that water temperature of about 20°, influent pH of 6 ～7 and DO of 1.0 mg/L - 1. 5 mg/L in the aerobic compartment. Under these conditions, COD, BODs,NH+4-N, and TN were removed effectively in HMBR and the average removal efficiencies were 94.5%,99.3%, 99.4% and 84.7%, respectively. SS and coliforms were both below the detection limits in the permeate of UF membrane module, and turbidity was less than 1NTU.The treated effluent meets the Miscellaneous Domestic Water Quality Standard (CJ25.1 - 89), and can be reused multipurposely such as watering of green belts, cleaning and toilet flushing water after disinfection.