Photocatalytic oxidation kinetics of thiophene in n-octane/water extraction system was studied with fluorine and ferric ion codoped nano-TiO2(nano-F/Fe3+/TiO2)powders used as the photocatalyst.Effects of initial concentration of thiophene and additional dosage of F-/Fe3+/TiO2 on the reaction rate constant and half-life were investigated.The results showed that the appropriately added dosage of F-/Fe3+/TiO2 was 0.1 g in the 100-mL reaction system and the photooxidative kinetics of thiophene in the presence of F-/Fe3+/TiO2 catalyst was of first-order with a rate constant of 0.6508 h-1 and a half-life of 1.0651 h.The desulfurization rate of thiophene was 98.1% in 5 h and the sulfur content could be reduced from 800 ppm to 15 ppm The reaction rate constant increased with a decreasing initial concentration of thiophene.